成人直播

个人简介

魏超，理学博士，硕士生导师，成人直播 副教授。主要从事干细胞的表观、三维染色质结构与相分离的调控机制等方面研究。近年来在Cell Res, NAT STRUCT MOL BIOL, NAT COMMUN, PROTEIN CELL, Stem Cell Rep, MOL MED, Clinical Epigenetics 等发表多篇文章（1篇IF>40，2篇IF >15 ）。主持/承担了国家自然科学面上项目，国家自然科学青年项目，广东省自然科学基金-面上项目与国家重点研发计划。

学术成果

1. Wei C#, Jia L#, Huang XN#, Tan J#, Wang ML, Niu J, Hou YP, Sun J, Zeng PGH, Wang J, Qing L, Ma L, Liu XY, Tang XX, Li FJ, Jiang SS, Liu JX, Li TT, Fan LL, Sun YJ, Gao JT, Li C, Ding JJ. CTCF organizes inter-A compartment interactions through RYBP-dependent phase separation. Cell Research. 2022, 32, 744-760.

2. Hong Y#, Dai RR#, Li XL #, Xu H and Wei C*. Polycomb protein RYBP facilitates super-enhancer activity. Molecular Medicine, 2024, 30(1). 

3. Hong Y#, Li# XL, Li J#, He QY, Huang MB, Tang YB, Chen X, Chen J, Tang KJ and Wei C*. H3K27ac acts as a molecular switch for doxorubicin-induced activation of cardiotoxic genes. Clinical Epigenetics (1868-7075). 2024, 16(1).

4. Huang XN#, Wei C#, Li FJ#, Jia LM, Zeng PGH, Li JH, Tan J, Sun TF, Jiang SS, Jia Wang J, Tang XX, Zhao QQ, Liu B, Rong LM, Li C, Ding JJ. PCGF6 regulates stem cell pluripotency as a transcription activator via super-enhancer dependent chromatin interactions. Protein & Cell, 2019, 10, 709-725.

5. Wang# J, Wu XG#, Wei C#, Huang X, Ma Q, Huang XN, Faiola F, Guallar D, Fidalgo M, Huang TY, Peng D, Chen L, Yu HP, Li XY, Sun JY, Liu XY, Cai XX, Chen X, Wang L, Ren J, Wang JL* and Ding JJ*. YY1 Positively Regulates Transcription by Targeting Promoters and Super-Enhancers through the BAF Complex in Embryonic Stem Cells, 2018, Stem Cell Rep 10, 1324-1339. 

6. Wei C#, Li X#, Zhang PF #, Zhang Y, Liu T, Jiang SS, Han F and Zhang YH. Characterization of porcine partially reprogrammed iPSCs from adipose-derived stem cells. Reproduction, 2015, 149, 485-496.

7. Wei C, Liu X, Tao J, Wu RH, Zhang PF, Bian YN, Li YS, Fang FG, Zhang YH. Effects of vitamin C on characteristics retaining of in vitro-cultured mouse adipose-derived stem cells. 2014. In Vitro Cell Dev Biol Anim 50, 75-86.

8. Zhang Y #, Wei C#, Zhang PF, Li X, Liu T, Pu Y, Li YS, Cao ZB, Cao HG, Liu Y, Zhang XR, Zhang YH. Efficient Reprogramming of Naive-Like Induced Pluripotent Stem Cells from Porcine Adipose-Derived Stem Cells with a Feeder-Independent and Serum-Free System. Plos One 9.

9. Qu JL, Sun J, Zhao C, Liu XY, Zhang XY, Jiang SS,Wei C, Yu HP, Zeng XX, Fa LL, Ding JJ. Simultaneous profiling of chromatin architecture and transcription in single cells. Nature Structural & Molecular Biology. (2023) 30, 1393-+.

10. Sun J, Qu JL, Zhao C, Zhang XY, Liu XY, Wang J, Wei C, Liu XY, Wang ML, Zeng PGH, Tang XX, Ling XR, Qing L, Jiang SS, Chen JH, Chen TS, Kuang YL, Gao JH, Zeng XX, Huang DF, Yuan Y, Fan LL, Yu HP, Ding JJ. Precise prediction of phase-separation key residues by machine learning. (2024), Nature Communications,15(1) .

11. Tang XX, Zeng PGH, Liu KZ, Qing L, Sun YF, Liu XY, Lu LZ, Wei C, Wang J, Jiang SS, Sun J, Chang WK, Yu HP, Chen HB, Zhou JG, Xu CF, Fan LL, Miao YL, Ding JJ. The PTM profiling of CTCF reveals the regulation of 3D chromatin structure by O-GlcNAcylation.(2024), Nature Communications, 15(1).